Membrane Chromatography Market Expected to Grow at a Steady Rate

Pune, March 31, 2022 (GLOBE NEWSWIRE) — Chromatography is a laboratory technique that focuses on determining differences in the physical and chemical properties of various substances. Membrane chromatography uses a microfiltration membrane with functional ligand or antigens bound to the inner pore surface through the membrane structure to achieve highly selective separations via binding interactions. Depending on the separation material, certain membranes with a larger pore size are used. They have high link efficiency as well as fast throughput and scalability. Membrane chromatography is a well-known biological treatment technology that is frequently used in the capture of large particles like viruses and viral sectors, as well as polishing processes to remove DNA, protein impurities from host cells and viruses.

The main advantage of the membrane chromatography method is attributed to the short diffusion times, because the communications between molecules and the active sites of the membrane occur in convective through pores rather than passive fluid inside the pores. resin. Another interesting feature of these membrane devices for the biopharmaceutical industries is their single-use capability, as the elimination of cleaning and regeneration steps decreases the risk of contamination and production costs. Most maximum membrane chromatography devices, especially those for ion exchange, are made from regenerated cellulose. The advantages offered by membrane chromatography include high binding efficiency due to direct access to linking groups even at high flow rates, lower cost of operation, and high scalability and flexibility.

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The global membrane chromatography market is expected to witness strong growth in the coming years owing to the growing demand for biopharmaceuticals. The market is also benefiting from increased investments in research and development in the biopharmaceutical industry. The various advantages of membrane chromatography over traditional chromatography methods will also be a key factor in the increasing adoption of membrane chromatography methods. In addition to this, the growing regulatory study on cleaning validation of downstream purification processes will drive the growth of the global membrane chromatography market. The global membrane chromatography market is mainly driven by the growing demand for biopharmaceuticals and the growth of R&D projects in the biotechnology industry for the booming healthcare sector.

The membrane chromatography market is segmented on the basis of technique, product, operation, end user and region. On the basis of technique, the market is bifurcated into Affinity Membrane Chromatography, Hydrophobic Interaction Membrane Chromatography (HIMC) and Ion Exchange Membrane Chromatography wherein the Ion Exchange Membrane Chromatography segment would represent the significant share of the market. Ion exchange chromatography has several advantages such as disposable nature, fast processing, robustness, scalability, good ratio, reduced battery consumption and validation-free environment. Based on product, the market is divided into consumables and accessories. Consumables include capsules, cartridges, syringes, membrane discs and sheets.

Based on the mode of operation, the market is segmented into continuous flow membrane chromatography and bound elution membrane chromatography. Further, on the basis of end-user membrane chromatography market, it is divided into pharmaceutical and biopharmaceutical companies, CROs, academic and research institutes. In the coming period, the pharmaceutical and biopharmaceutical sector is expected to grow at a significant rate. Increased investment in R&D operations in the biopharmaceutical sector, as well as increased development of biologics are both contributing to growth.

North America is expected to dominate the market owing to the presence of the largest consumer market with high GDP. North America includes the United States, Canada and Mexico. The United States and Canada have well-structured and developing health systems. These countries also promote pharmaceutical research and development and therefore have very high health expenditures. Due to these policies, many companies around the world are encouraged to operate in this region.

The Asia-Pacific region also holds the majority of the membrane chromatography market share and is expected to witness growth due to the increase in the number of small players and rising awareness. China will remain among the fastest growing markets in this group of regional markets. Led by countries like Japan, Australia, India and South Korea in the Asia-Pacific market.

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COMPANY PROFILES (Company Overview, Products/Services Offered, Financial Performance, R&D Intensity, Marketing & Sales Intensity, Recent Developments, Analyst Corner)*

  1. Merck Millipore
  2. GE Healthcare
  3. Danaher
  4. Sartorius
  5. Thermo Fisher Scientific
  6. Asahi Kasei
  7. Restek
  8. 3M
  9. Cole Parmer
  10. Membrane solutions

RECENT DEVELOPMENTS

In 2017, Sartorius AG launched Sartobind cassettes

In 2018, the 3M company launched the Emphaze AEX hybrid purifier capsules.

In October 2019, Merck KGaA announced that it had invested in its global headquarters in Darmstadt for the construction of a new translational science center for its Healthcare business line as well as a new learning center. This investment allowed the company to increase its R&D activities.

In 2019, Thermo Fisher Scientific invested approximately $24 million in its Scottish site to expand its global biomanufacturing capabilities and meet demand for industry-leading biomanufacturing products.

In 2019, Sartorius AG entered into an agreement to acquire parts of Danaher’s Life Science portfolio, which is complementary to Sartorius’ laboratory and bioprocess business portfolio. This transaction is expected to be finalized in the first quarter of 2020.

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In 2020, Danaher Corporation completed the acquisition of the Biopharma business from the Life Sciences division of General Electric Company and renamed it Cytiva.

In August 2021, Sartorius AG announced that it had entered into a partnership with McMaster University to improve manufacturing processes for antibody and virus-based treatments for diseases such as COVID-19, cancers and genetic disorders. This helped the company improve its manufacturing process and increase production.

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